Obesity, Food Intake & CBD

Cannabidiol inhibits the hyperphagia induced by cannabinoid-1 or serotonin-1A receptor agonists.

Posted by Joe Pavlik on

Published: Pharmacol Biochem Behav. 2011 Apr;98(2):268-72. doi: 10.1016/j.pbb.2011.01.007. Epub 2011 Jan 14. Cannabidiol inhibits the hyperphagia induced by cannabinoid-1 or serotonin-1A receptor agonists. Scopinho AA, Guimarães FS, Corrêa FM, Resstel LB. Abstract Δ9-THC is a component of Cannabis sativa that increases food intake in animals and humans, an effect prevented by selective CB1 receptor antagonists. Cannabidiol (CBD) is another constituent of this plant that promotes several opposite neuropharmacological effects compared to Δ9-THC. CBD mechanisms of action are still not clear, but under specific experimental conditions it can antagonize the effects of cannabinoid agonists, block the reuptake of anandamide and act as...

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