Intervertebral Disc Degeneration & CBD

Protective Effects of Cannabidiol on Lesion-Induced Intervertebral Disc Degeneration

Posted by Joe Pavlik on

Published: PLoS One. 2014; 9(12): e113161. Protective Effects of Cannabidiol on Lesion-Induced Intervertebral Disc Degeneration João W. Silveira, Ana Carolina Issy, Vitor A. Castania, Carlos E. G. Salmon, Marcello H. Nogueira-Barbosa, Francisco S. Guimarães, Helton L. A. Defino, and Elaine Del Bel. Partha Mukhopadhyay, Editor Abstract Disc degeneration is a multifactorial process that involves hypoxia, inflammation, neoinnervation, accelerated catabolism, and reduction in water and glycosaminoglycan content. Cannabidiol is the main non-psychotropic component of the Cannabis sativa with protective and anti-inflammatory properties. However, possible therapeutic effects of cannabidiol on intervertebral disc degeneration have not been investigated yet. The present study investigated...

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