Anti-Myeloma Activities & CBD

Cannabinoids synergize with carfilzomib, reducing multiple myeloma cells viability and migration.

Posted by Joe Pavlik on

Published: Oncotarget. 2016 Oct 18. doi: 10.18632/oncotarget.12721. [Epub ahead of print] Cannabinoids synergize with carfilzomib, reducing multiple myeloma cells viability and migration. Nabissi M, Morelli MB, Offidani M, Amantini C, Gentili S, Soriani A, Cardinali C, Leoni P, Santoni G. Abstract Several studies showed a potential anti-tumor role for cannabinoids, by modulating cell signaling pathways involved in cancer cell proliferation, chemo-resistance and migration. Cannabidiol (CBD) was previously noted in multiple myeloma (MM), both alone and in synergy with the proteasome inhibitor bortezomib, to induce cell death. In other type of human cancers, the combination of CBD with Δ9-tetrahydrocannabinol (THC) was found...

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