Bladder Dysfunction & CBD

An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis.

Posted by Joe Pavlik on

Published: Mult Scler. 2004 Aug;10(4):425-33. An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis. Brady CM, DasGupta R, Dalton C, Wiseman OJ, Berkley KJ, Fowler CJ. Abstract The majority of patients with multiple sclerosis (MS) develop troublesome lower urinary tract symptoms (LUTS). Anecdotal reports suggest that cannabis may alleviate LUTS, and cannabinoid receptors in the bladder and nervous system are potential pharmacological targets. In an open trial we evaluated the safety, tolerability, dose range, and efficacy of two whole-plant extracts of Cannabis sativa in patients with advanced MS and refractory LUTS. Patients took extracts containing...

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